i'm not in that niche... but those women are hogs and morbidly obese... i don't think thats really what that niche is supposed to be... or what those people are searching for.
personally, i would tell you to forget about most of the advice here. first and foremost, you have to understand what users are searching for exactly (for the bulk of them anyway) and figure out what content is best representative of what they are looking for. FROM THERE.... you start looking at ways to increase / improve clicks to pay sites, look at conversions, which sponsors perform better etc.
design elements, layout etc is often on of the most counter-intuitive aspects of this biz. i wouldn't think too hard on that initially.
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