I've no experience with mailing lists but if you have lets say a big tits paysite and collect the join emails from that, then I would say your newsletter thing should have like daily or weekly pic updates from other big tits sponsors to upsell with and in the email just have like "click here to join X site for more of these pics". And of course an opt-out link at the bottom.
There's actually a big thread on here somewhere where someone with a big mailing list explains exactly how to do the whole thing..
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