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The show is actually based on a book by David Simon (the Wire creator) called The Corner. It was also an HBO miniseries. When Simon was a reporter for the Baltimore Sun he spent a year observing one corner in a ghetto in Baltimore and wrote about it. So based on what he saw there it is pretty realistic. I'm sure there are some thing done for the sake of a show and dramatic effect, but overall it is right on point according to Simon.
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