Have a look at how PicHunter is doing it. I think they did a great job.
For example:
Busty blonde hottie Tommie Joe strips and spreads in high heels and sexy lingerie - Pichunter
Shawna Lenee Exposes Her Tits and Perky Nipples - Pichunter
Granted there could be some additional work with imagemagick on the thumbs, but the fluid design works well on various devices.